Inverse sampling and triangular sequential designs to compare a small proportion with a reference value.

Título inglés	Inverse sampling and triangular sequential designs to compare a small proportion with a reference value.
Título español	Muestreo inverso y diseños secuenciales triangulares para comparar una pequeña proporción con un valor de referencia.
Autor/es	Moreno, Víctor ; Martín, Isaac ; Torres, Ferrán ; Horas, Manuel ; Ríos, José ; González, Juan R.
Organización	Inst. Catalán Oncol., Barcelona, España;Lab. Bioestad. Epidemiol. Fac. Med. Univ. Autòn. Barcelona, Barcelona, España;Dep. Estad. Econometr. Univ. Carlos III, Madrid, España
Revista	0210-8054
Publicación	2002, 26 (1-2): 259-271, 12 Ref.
Tipo de documento	articulo
Idioma	Inglés
Resumen inglés	Inverse sampling and formal sequential designs may prove useful in reducing the sample size in studies where a small population proportion p is compared with a hypothesized reference proportion p0. These methods are applied to the design of a cytogenetic study about chromosomal abnormalities in men with a daughter affected by Turner's syndrome. First it is shown how the calculated sample size for a classical design depends on the parameterization used. Later this sample size is compared with the required sample size in an inverse sampling design and a triangular sequential design using four different parameterizations (absolute differences, log-odds ratio, angular transform and Sprott's transform). The expected savings in sample size, when the alternative hypothesis is true, are 20% of the fixed sample size for the inverse sampling design and 40% for the triangular sequential design.
Clasificación UNESCO	120905
Palabras clave español	Bioestadística ; Diseño de experimentos ; Tamaño muestral ; Muestreo secuencial ; Muestreo inverso
Código Z-Math	Zbl 1040.62067
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